Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ (±)-Verapamil, Hydrochloride
A papaverine derivative that blocks Ca2+ channels (principally the L-type) in smooth and cardiac muscle cells.
MilliporeSigma™ Calbiochem™ JNK Inhibitor I, (L)-Form, Cell-Permeable
The JNK Inhibitor I, (L)-Form, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Epoxomicin, Synthetic
Epoxomicin, Synthetic, CAS 134381-21-8, is a potent, specific, and irreversible inhibitor of chymotrypsin-like, trypsin-like, and peptidyl-glutamyl peptide hydrolyzing activities of the proteasome.
MilliporeSigma™ Calbiochem™ Cdc42/Rac1 Dual Inhibitor, AZA1
A cell-permeable compound that suppresses upregulation of GTP-bound Rac1 and Cdc42. Inhibits prostate cancer cells migration by decreasing cellular F-/G-actin ratio.
MilliporeSigma™ Calbiochem™ Nα-Benzyloxycarbonyl-L-lysine Thiobenzyl Ester, Hydrochloride
Highly sensitive substrate for trypsin-like enzymes and granule-associated serine esterase.
MilliporeSigma™ Calbiochem™ InSolution™ GSK-3 Inhibitor XVI, CHIR99021
InSolution™ GSK-3 Inhibitor XVI, CHIR99021, CAS 252917-06-9, is a 25 mM solution in DMSO. A cell-permeable, ATP-competitive inhibitor of GSK-3 (IC50 = 10 & 6.7 nM for GSK-3α and GSK-3β, respectively).
MilliporeSigma™ Calbiochem™ GGTI-286
A potent, cell-permeable, and selective inhibitor of GGTase I.
MilliporeSigma™ Calbiochem™ Ginkgolic Acid (15:1)
A cell-permeable anacardic acid analog that inhibits protein SUMO .
MilliporeSigma™ Calbiochem™ Glucagon-Like Peptide 1 Receptor Agonist II
A pyrimidine small molecule that acts as a GLP-1 allosteric agonist that induces cAMP signaling in HEK293 cells expressing the GLP-1 receptor with EC50
MilliporeSigma™ Calbiochem™ PKG Iα Inhibitor, Cell-Permeable
The PKG Iα Inhibitor, Cell-Permeable controls the biological activity of PKG Iα. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ GW1929
A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).
MilliporeSigma™ Calbiochem™ Heat Shock Protein Inhibitor I
Heat Shock Protein Inhibitor I, CAS 218924-25-5 blocks the induction of HSP70, HSP72, and HSP105. Blocks the development of thermotolerance in a dose-dependent manner.
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphate, Sodium Salt
Important intracellular second messenger implicated in the action of nitric oxide in many cell types.
MilliporeSigma™ Calbiochem™ HDL Receptor SR-BI Inhibitor, BLT-1
The HDL Receptor SR-BI Inhibitor, BLT-1, also referenced under CAS 321673-30-7, controls the biological activity of HDL Receptor SR-B. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ GPR43 (FFA2) Agonist
The GPR43 (FFA2) Agonist controls the biological activity of GPR43. This small molecule/inhibitor is primarily used for Biochemicals applications.